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Project information
Using MALDI-TOF mass spectrometry for identification of molecular patterns in relapsed multiple myeloma patients

Information

This project doesn't include Faculty of Arts. It includes Faculty of Medicine. Official project website can be found on muni.cz.
Project Identification
NU21-03-00076
Project Period
5/2021 - 12/2024
Investor / Pogramme / Project type
Ministry of Health of the CR
  • Programme NU (2020 - 2026)
  • Subprogram 1 - standard
MU Faculty or unit
Faculty of Medicine
Cooperating Organization
University Hospital Brno-Bohunice
  • Responsible person prof. MUDr. Luděk Pour, Ph.D.

Multiple myeloma is the second most common hematological malignancy
of the elderly. Median age at diagnosis is 65. Bone marrow transplants as
well as new drugs (immunomodulatory drugs, proteasome inhibitors and
monoclonal antibodies) significantly increased survival of MM patients in
the past 10 years. Nevertheless, most patients still relapse. This project will
aim to analyze small molecules in peripheral blood as well as bone marrow
microenvironment of MM patients who underwent stem cell transplant and
new drugs treatments using next generation sequencing and mass
spectrometry to create a diagnostic tool based on prediction by artificial
neural networks that will help identify patients in high risk of relapse.

Sustainable Development Goals

Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.

Sustainable Development Goal No. 3 – Good health and well-being Sustainable Development Goal No. 4 – Quality education Sustainable Development Goal No. 5 – Gender equality Sustainable Development Goal No. 17 – Partnerships for the goals

Publications

Total number of publications: 24

2025

2024

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