Project information
CIISB - Czech Infrastructure for Integrative Structural Biology
(CIISB)
- Project Identification
- LM2023042
- Project Period
- 1/2023 - 12/2026
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- Large Infrastructures for Research, Development and Innovation
- MU Faculty or unit
- Central European Institute of Technology
- Project Website
- https://www.ciisb.org/
- Cooperating Organization
-
Institute of Biotechnology CAS
- Responsible person Ing. Jan Dohnálek, PhD.
The Czech Infrastructure for Integrative Structural Biology (CIISB) is a distributed national infrastructure, which consists of two nodes, one represented by CEITEC (Central European Institute of Technology, Brno) and second by BIOCEV (Biotechnology and Biomedicine Centre of the Academy of Sciences and Charles University, Vestec near Prague). CIISB offers access to 10 core facilities; five of them are part of the Centre of Structural Biology and one of the Mendel Centre of Genomics and Proteomics of Plants of CEITEC Masaryk University and four of the Centre of Molecular Structure of the Institute of Biotechnology AS CR in the BIOCEV Centre.
All CIISB core facilities are in the full operational phase. Projects as OP RDI (Start-up) supported the construction phase, and the built capacities were made available by both CIISB nodes in the form of Open Access to internal and external users. In its construction phase, CIISB (2011-2015) was the Associated National Center of the pan-European research infrastructure INSTRUCT. In 2016, following the completion, putting into operation, and subsequent international evaluation, CIISB became a fully-fledged Instruct-CZ Centre for this distributed infrastructure.
Sustainable Development Goals
Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.
Publications
Total number of publications: 139
2025
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Proteomic Insights into the Adaptation of Acidithiobacillus ferridurans to Municipal Solid Waste Incineration Residues for Enhanced Bioleaching Efficiency
Journal of Proteome Research, year: 2025, volume: 24, edition: 5, DOI
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Proteomic profiles of patients suffering from subarachnoid hemorrhage
Year: 2025, type: Conference abstract
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Pseudomonas rossensis sp. nov., a novel psychrotolerant species produces antimicrobial agents targeting resistant clinical isolates of Pseudomonas aeruginosa
Current Research in Microbial Sciences, year: 2025, volume: 8, edition: 2025, DOI
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Psychrotolerant enterobacters inhabiting the gut of Antarctic fishes of the family Nototheniidae and description of Enterobacter hoffmannii subsp. nototheniae subsp. nov.
Czech Polar Reports, year: 2025, volume: 15, edition: 2, DOI
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Replication and transcription regulator Rta of Epstein-Barr virus - functional and structural implications for new antiviral strategy
Year: 2025, type: Conference abstract
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Search for Mutations Connected With Non-Response to Anti-EGFR Therapy in mCRC in the Morphologically Defined Regions of Primary Tumours
Cancer Medicine, year: 2025, volume: 14, edition: 9, DOI
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Solving the mysteries of novel two-domain lectins from human pathogens
Year: 2025, type: Appeared in Conference without Proceedings
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Specific inhibition of fibroblast growth factor receptor 1 signaling by a DNA aptamer
MOLECULAR THERAPY-NUCLEIC ACIDS, year: 2025, volume: 36, edition: 1, DOI
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Structural basis of bis-quinolinium ligands binding to quadruplex-duplex hybrids from PIM1 oncogene
Nucleic Acids Research, year: 2025, volume: 53, edition: 17, DOI
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Supramolecular covalency of halogen bonds revealed by NMR contact shifts in paramagnetic cocrystals
Chemical Science, year: 2025, volume: 16, edition: 43, DOI