Multiple levels of meaning in DNA sequences, and one more

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Authors

TRIFONOV Eduard Nikolajevič VOLKOVICH, Zeev FRENKEL Zakharia M

Year of publication 2012
Type Article in Periodical
Magazine / Source Ann NY Acad Sci
MU Faculty or unit

Central European Institute of Technology

Citation
Web http://onlinelibrary.wiley.com/doi/10.1111/j.1749-6632.2012.06589.x/abstract
Doi http://dx.doi.org/10.1111/j.1749-6632.2012.06589.x
Field Genetics and molecular biology
Keywords sequence codes; overlapping codes; gene splicing; nucleosome positioning; genome inflation code; codon usage
Description If we define a genetic code as a widespread DNA sequence pattern that carries a message with an impact on biology, then there are multiple genetic codes. Our data are consistent with the hypothesis that expansion of simple tandem repetition of certain aggressive triplets has been a characteristic of life from its emergence. Such expanding triplets appear to be the major factor underlying observed codon usage biases.
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