Thermostable FGF2 Polypeptide, Use Thereof

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Authors

DVOŘÁK Petr KREJČÍ Pavel BÁLEK Lukáš EISELLEOVÁ Lívia KONEČNÁ Žaneta DVOŘÁK Pavel BEDNÁŘ David BREZOVSKÝ Jan ŠEBESTOVÁ Eva CHALOUPKOVÁ Radka ŠTĚPÁNKOVÁ Veronika VAŇÁČEK Pavel PROKOP Zbyněk DAMBORSKÝ Jiří BOSÁKOVÁ Michaela

Year of publication 2020
Type Patent
MU Faculty or unit

Faculty of Science

Publisher European Patent Office
State Germany
Patent's number EP3380508
Web https://worldwide.espacenet.com/patent/search/family/054754475/publication/EP3380508B1?q=pn%3DEP3380508B1
Description The present invention relates to engineered Fibroblast Growth Factor 2 (FGF2, bFGF) having improved thermal stability compared to the wild-type and the use thereof in the cell biology research, regenerative medicine and related medical applications or cosmetics. The present invention further relates to a culture medium comprising FGF2 suitable for culturing a human pluripotent stem cells involving both human embryonic stem cells and induced pluripotent stem cells.
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