Functional Plasma Polymerized Surfaces for Biosensing

This publication doesn't include Faculty of Arts. It includes Central European Institute of Technology. Official publication website can be found on muni.cz.

Authors

MAKHNEVA Ekaterina BARILLAS Laura FARKA Zdeněk PASTUCHA Matěj SKLÁDAL Petr WELTMANN Klaus-Dieter FRICKE Katja

Year of publication 2020
Type Article in Periodical
Magazine / Source ACS Applied Materials & Interfaces
MU Faculty or unit

Central European Institute of Technology

Citation
Web https://pubs.acs.org/doi/10.1021/acsami.0c01443
Doi http://dx.doi.org/10.1021/acsami.0c01443
Keywords atmospheric-pressure plasma-induced polymerization; functional polymers; chemical composition; thin films; biosensing
Description The capabilities of biosensors for fast, economic, and user-friendly analysis of complex samples has led to the exploitation of analytical devices for detection, quantification, and monitoring of specific chemical species for various applications. For a sufficiently high surface reactivity toward the adopted bioreceptors, a thin functional layer is required to enable coupling of the target biomolecules and to provide good stability in the presence of a sample matrix. In this work, the generation of water-stable oxygen-rich plasma polymerized (pp) films deposited by atmospheric-pressure jet plasma for reliable immobilization of biomolecules is presented. Three types of pp films were developed and characterized. All of the obtained pp films were successfully used as a matrix layer in the SPR immunosensors, which provided excellent level of sensitivity, stability, and regenerability. The achieved results show that atmospheric pressure plasma-induced polymerization is a powerful alternative method for the preparation of matrix layers for a wide range of applications in the biological field.
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