Phenotype dynamics and its correlates in patients treated by paroxetine

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Authors	ŽOURKOVÁ Alexandra HADAŠOVÁ Eva PILAŘOVÁ Lucie KULÍSKOVÁ Olga ROBEŠ Miroslav
Year of publication	2003
Type	Article in Periodical
Magazine / Source	European Neuropsychopharmacology
MU Faculty or unit	Faculty of Medicine
Citation
Field	Psychiatry, sexuology
Keywords	paroxetine-CYP2D6-genotype-phenotype-efficacy-safety
Description	Study was explore in two double-blind trials the relationship between the genetic backround and cytochrome P450 CYP2D6 metabolic capacity with regard to the efficacy and drug safety of treatment with paroxetinem a strong CYP2D6 capacity inhibitor
Related projects:	Plasticity of Regulatory Mechanisms of the Central Nervous Systems