Anxiogenic-like effect of ecstasy in mice on conflict social interactions

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Authors	ŠULCOVÁ Alexandra LANDA Leoš ŠLAIS Karel
Year of publication	2006
Type	Article in Proceedings
Conference	Final programme and book abstracts - International Anxiety Disorders Conference 2006
MU Faculty or unit	Faculty of Medicine
Citation
Field	Pharmacology and pharmaceutical chemistry
Keywords	anxiety - ecstasy - social interaction - mice
Description	The most significant changes measured in timid singly-housed male mice on paired interation with non-aggressive group-housed partners after acutely given ecstasy were in increase of defensive-escape behaviour and decrease of sociable activities (just the highest dose stimulated significantly walking), suggesting anxiogenic-like drug effects.
Related projects:	The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.