Vliv polymorfismu C5266T v genu pro nNOS na variabilitu v srdečním intervalu.

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Title in English Influence of C5266T polymorphism in nNOS gene on inter-beat interval variability
Authors

JÍRA Miroslav ZÁVODNÁ Eva HONZÍKOVÁ Nataša NOVÁKOVÁ Zuzana VAŠKŮ Anna IZAKOVIČOVÁ HOLLÁ Lydie FIŠER Bohumil

Year of publication 2007
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Citation
Description Reduced inter-beat interval variability represents independent indicator of adverse prognosis in patients after myocardial infarction. The aim of this study was to evaluate association of single nucleotide polymorphism C5266T in gene encoding nNOS with heart period variability in men. We found significant association of C5266T polymorphism in gene encoding nNOS with heart period variability. The presence of allele T represents protective factor against sympathetic overactivity.
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