Correlation Study of Optimized Voxel-Based Morphometry and H MRS in Patients With Mesial Temporal Lobe Epilepsy and Hippocampal Sclerosis.

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Authors	BRÁZDIL Milan MAREČEK Radek FOJTÍKOVÁ Dagmar MIKL Michal KUBA Robert KRUPA Petr REKTOR Ivan
Year of publication	2009
Type	Article in Periodical
Magazine / Source	Human Brain mapping
MU Faculty or unit	Faculty of Medicine
Citation
Field	Neurology, neurosurgery, neurosciences
Keywords	mesial temporal lobe epilepsy; hippocampal sclerosis; thalamus; MR spectroscopy
Description	To assess whether structural and metabolic brain abnormalities are correlated in MTLE/HS syndrome. Optimized voxel-based morphometry (VBM) of gray matter concentration (GMC) and gray matter volume (GMV) and proton magnetic resonance spectroscopy measurements from both-sided hippocampal and thalamic regions were performed in 20 MTLE/HS patients and 20 sex- and age-matched healthy controls.
Related projects:	The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.