Revisiting the planarity of nucleic acid bases: Pyramidilization at glycosidic nitrogen in purine bases is modulated by orientation of glycosidic torsion
| Authors | |
|---|---|
| Year of publication | 2009 |
| Type | Article in Periodical |
| Magazine / Source | Nucleic Acids Research |
| MU Faculty or unit | |
| Citation | |
| Field | Biophysics |
| Keywords | bases of nucleic acids; molecular dynamics; NMR; quantum chemistry |
| Description | We describe a novel, fundamental property of pyramidilization at the N1/9 sites of purine and pyrimidine bases. The study combines analyses of ultra-highresolution X-ray structures together with quantum chemical calculations, molecular dynamics simulations, and published solution nuclear magnetic resonance data. |
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