Orthogonal Photocleavage of a Monochromophoric Linker

• Authors: KAMMARI Laxminarayana; ŠOLOMEK Tomáš; NGOY Bokolombe Pitchou; HEGER Dominik; KLÁN Petr
• Year of publication: 2010
• Type: Article in Periodical
• Magazine / Source: Journal of the American Chemical Society
• MU Faculty or unit: Faculty of Science
• web: http://pubs.acs.org/doi/abs/10.1021/ja1047736
• Field: Organic chemistry
• Keywords: Photochemistry; protecting groups.
• Description: The 4-acetyl-2-nitrobenzyl moiety, substituted in both benzylic and phenacyl positions with leaving groups, has been proposed as a monochromophoric photocleavable linker. The attached groups can be disconnected selectively and orthogonally upon irradiation.

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