Ecotoxicity and genotoxicity assessment of cytotoxic antineoplastic drugs and their metabolites

Investor logo

Warning

This publication doesn't include Faculty of Arts. It includes Faculty of Science. Official publication website can be found on muni.cz.
Authors

ZOUNKOVÁ Radka KOVALOVÁ Lubomíra BLÁHA Luděk DOTT Wolfgang

Year of publication 2010
Type Article in Periodical
Magazine / Source Chemosphere
MU Faculty or unit

Faculty of Science

Citation
Field Environment influence on health
Keywords Cytostatics; Cytotoxic drugs; Metabolites; Ecotoxicity; Cenotoxicity; Chronic effects
Description This study reported ecotoxicity and genotoxicity of three widely used cytostatic agents (5-fluorouracil (5-FU), cytarabine (CYT) and gemcitabine (GemC) and their major human metabolites, i.e. alpha-fluoro-beta-alanine (FBAL), uracil-1-beta-D-arabinofuranoside (AraU) and 2',2'-difluorodeoxyuridine (dFdU)).
Related projects:

You are running an old browser version. We recommend updating your browser to its latest version.