An analysis of residue alkylphenols and bisphenol A using liquid chromatography-tandem mass spectrometry

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Publikace nespadá pod Filozofickou fakultu, ale pod Přírodovědeckou fakultu. Oficiální stránka publikace je na webu muni.cz.

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PERNICA Marek ŠIMEK Zdeněk

Rok publikování 2019
Druh Článek ve sborníku
Konference MENDELNET 2019: PROCEEDINGS OF 26TH INTERNATIONAL PHD STUDENTS CONFERENCE
Fakulta / Pracoviště MU

Přírodovědecká fakulta

Citace
www https://mendelnet.cz/artkey/mnt-201901-0116_An-analysis-of-residue-alkylphenols-and-bisphenol-A-using-liquid-chromatography-tandem-mass-spectrometry.php?back=/magno/mnt/2019/mn1.php?secid=4
Klíčová slova blank; blank contamination; LC-MS; alkylphenols; bisphenol A
Popis Bisphenol A (BPA) and alkylphenols (APs) such as 4-tert-octylphenol (4-t-OP) and mixture of nonylphenol isomers (iso-NP) are frequent contaminants of various environmental analyses. Analyse of various blanks is a serious problem in the residue analysis. Secondary contamination of analysed samples can come from laboratory air, septa vials, solvents and other chemicals used. Plastic tubes and connections could be another important source of sample contamination. This can be a problem especially in determination of alkylphenols and bisphenol A at low environmentally relevant concentrations. The analytical method for determination of residues of pollutants in water samples using solid phase extraction (SPE) followed by liquid chromatography-tandem mass spectrometry (LC-MS/MS) is presented here. In principle, alkylphenols can be analysed without derivatization. However, pre-column derivatization with 5-(dimethylamino) naphthalene-1-sulfonyl chloride (dansylchloride, DNSC) improves the sensitivity and selectivity of LC-MS/MS analysis. The instrumental blank for all compounds is under the limit of detection (LOD). The system contamination was maintained about 0.5 ng (reagent blank), and below 0.05 mu g/L for the glass SPE columns and below 0.1 mu g/L for the plastic columns (procedure blank).
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