Informace o projektu
CIISB - Česká infrastruktura pro integrativní strukturní biologii
(CIISB)
- Kód projektu
- LM2023042
- Období řešení
- 1/2023 - 12/2026
- Investor / Programový rámec / typ projektu
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Ministerstvo školství, mládeže a tělovýchovy ČR
- Velké infrastruktury pro výzkum, vývoj a inovace
- Fakulta / Pracoviště MU
- Středoevropský technologický institut
- Spolupracující organizace
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Biotechnologický ústav AV ČR, v.v.i.
- Odpovědná osoba Ing. Jan Dohnálek, PhD.
The Czech Infrastructure for Integrative Structural Biology (CIISB) is a distributed national infrastructure, which consists of two nodes, one represented by CEITEC (Central European Institute of Technology, Brno) and second by BIOCEV (Biotechnology and Biomedicine Centre of the Academy of Sciences and Charles University, Vestec near Prague). CIISB offers access to 10 core facilities; five of them are part of the Centre of Structural Biology and one of the Mendel Centre of Genomics and Proteomics of Plants of CEITEC Masaryk University and four of the Centre of Molecular Structure of the Institute of Biotechnology AS CR in the BIOCEV Centre.
All CIISB core facilities are in the full operational phase. Projects as OP RDI (Start-up) supported the construction phase, and the built capacities were made available by both CIISB nodes in the form of Open Access to internal and external users. In its construction phase, CIISB (2011-2015) was the Associated National Center of the pan-European research infrastructure INSTRUCT. In 2016, following the completion, putting into operation, and subsequent international evaluation, CIISB became a fully-fledged Instruct-CZ Centre for this distributed infrastructure.
Cíle udržitelného rozvoje
Masarykova univerzita se hlásí k cílům udržitelného rozvoje OSN, jejichž záměrem je do roku 2030 zlepšit podmínky a kvalitu života na naší planetě.
Publikace
Počet publikací: 155
2025
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A newly developed cobalt(II) complex derived from a thiourea derivative and assessment of its potential bioapplicability against plant root pathogens
JOURNAL OF COORDINATION CHEMISTRY, rok: 2025, ročník: 78, vydání: 22, DOI
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AFM application across the life sciences field and its combination with special techniques
Rok: 2025, druh: Konferenční abstrakty
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Anti-Cancer Potential of a new Derivative of Caffeic Acid Phenethyl Ester targeting the Centrosome
Redox Biology, rok: 2025, ročník: 81, vydání: April 2025, DOI
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Arg-C Ultra Simplifies Histone Preparation for LC-MS/MS
Analytical chemistry, rok: 2025, ročník: 97, vydání: 24, DOI
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Article Navigation Journal Article CDK7–CDK11 axis in spliceosome regulation and pre-mRNA splicing
Nucleic Acids Research, rok: 2025, ročník: 53, vydání: 22, DOI
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Automated Engineering Protein Dynamics via Loop Grafting: Improving Renilla Luciferase Catalysis
ACS Catalysis, rok: 2025, ročník: 15, vydání: 4, DOI
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Combined action of suicide gene exosomes from pancreatic cancer-associated fibroblasts and from mesenchymal stem cells as a pancreatic ductal adenocarcinoma treatment approach
Cancer Cell International, rok: 2025, ročník: 26, vydání: DEC 20 2025
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CRISPR-Cas10-Assisted Structural Modification of Staphylococcal Kayvirus for Imaging and Biosensing Applications
ACS Synthetic Biology, rok: 2025, ročník: 14, vydání: 8, DOI
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Cyclodextrin-Based Metal-Organic Framework as an Application Platform for Bioactive Ruthenium(III) Complexes
Inorganic Chemistry, rok: 2025, ročník: 64, vydání: 22, DOI
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DIA-MS identified transmembrane glycoprotein GPNMB as a candidate predictive biomarker and potentially a therapeutic target in metastatic renal cell carcinoma
Rok: 2025, druh: Konferenční abstrakty